Bayer AG provides customers worldwide with health care, nutrition, and other products and services. The holding company encompasses the Bayer HealthCare AG, Bayer CropScience AG, Bayer MaterialScience AG, Bayer Business Services GmbH, Bayer Technology Services GmbH, and Bayer Industry Services GmbH and Company businesses. Bayer HealthCare develops and manufactures disease prevention, diagnosis, and treatment products. It includes pharmaceuticals, consumer care, diagnostics, diabetes care, and animal divisions. It is known for the Kogenate (R), Trasylol (R), Adalat (R), Cipro (R), Alka-Seltzer (R), and One-A-Day (R) product lines. Bayer CropScience develops crop protection and non-agricultural pest control products. Bayer MaterialScience develops high-performance materials. It produces polycarbonates, polyurethanes, coatings, adhesives, sealants, thermoplastic polyurethanes, and inorganic base chemicals. The Bayer Business Services is a global IT services unit. Bayer Technology Services focuses on process development and plant engineering, construction, and optimization. Bayer Industry Services manages Germany's largest chemical park network. Bayer AG maintains facilities across Europe, the Americas, Asia, Africa, and the Middle East. Bayer markets over 5,000 products. Bayer was founded in 1863 by Friedrich Bayer and Johann Friedrich Weskott. The firm trademarked the Aspirin (R) pain killer in 1899. Friedr. Bayer & Company merged with other companies to form I.G. Farbenindustrie AG in 1925. The firm was re-established as Farbenfabriken Bayer AG in 1951. It was renamed Bayer AG in 1972. Bayer was listed on the Franfurt Stock Exchange in 1953. It also is listed on the New York Stock Exchange.