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Article

Title: A Breakthrough in Building Life from Scratch

Author: Kaplan, Karen Article Type: Product Analysis
Source: San Francisco Chronicle, pA9(1) Publication Date: Jun 29, 2007
URL of Publication: http://www.sfgate.com

Craig Venter and his colleagues at the J. Craig Venter Institute have converted one species of bacterium into another by replacing all of its DNA, a critical step toward their ultimate goal of designing entire organisms from scratch, according to a study published Thursday. Venter did not back the long effort by government scientists to decode the human genome, and he was able to reach the achievement at a private company in only two years. He said the DNA transplants done had worked to date only in very closely related species of bacterium. Venter and his associates say considerable time will pass before the transfer of genomes between other organisms is fully understood. As part of the study, the researchers removed DNA from Mycoplasma mycoides and inserted it into Mycoplasma capricolum. Both bacteria are causes of respiratory disease and other ailments in goats, and they were selected because they have comparatively small genomes and they grow quickly. This allows the scientists to collection data in just days. The procedure has similarity to somatic cell nuclear transfer, but only the blueprint is sent in the procedure done by Venter and his associates.

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