In 2007, according to plan, the largest scientific instrument ever built will come to life in a labyrinthine underground complex in Switzerland, near Geneva. The Large Hadron Collider (LHC), will double-beam protons in opposite directions around a 27-kilometer-long circular tunnel. The beams will travel at almost the speed of light, collide head-on, and produce a shower of subatomic fragments expected by scientists to include exotic, never-before-seen particles that could change our fundamental knowledge of the universe. This is the hope of scientists at the European Union Organization for Nuclear Research (CERN), which will run the LHG. No supercomputer can handle the storage and analysis of the 15 million gigabytes per year of data to be generated, but the scientists will use a huge collection of computing grids built from the high-powered computer systems in almost 200 research centers globally, which will be networked and configured to function as one parallel processing systems. CERN and its partner universities, research agencies, and companies will use the experience of the LHC grid to create a massively global grid infrastructure. Under the leadership of CERN, the group wants to make the new global grid a tool able to solve many problems in science, engineering, and industry. The initiative is called Enabling Grids for E-science (EGEE), and its grid is made up mostly of multiple PC clusters. Among topics covered are EGEE's high throughput goals, enabling products from leading computer vendors, background of the EGEE project beginning in 2004, applications running on the EGEE currently (including drug simulations running on the EGEE grid), and issues related to maintenance of the reliability of the grid.