Electronic Sensor Technology's zNose Model 4200 is a new chemical profiling system that directly quantifies odor concentration and intensity with an integrated GC sensor. ZNose uses a solid-state surface-acoustic-wave (SAW) sensor with electronically variable sensitivity and can identify chemical species in vapors inside cargo containers. zNose also determines chemical concentrations in 10 s with pictogram sensitivity. The zNose is appropriate for sampling any accessible container, but presently has immediate significance for Americas ports. Cargo containers are definitely an immediate danger as a way for terrorist attacks or for smuggling of weapons of mass destruction. The zNose is portable with an ultra high-speed chromatography column, a solid-state sensor, a programmable gate-array multiprocessor, and an integrated vapor preconcentrator. The zNose sensor system generates high-resolution, 2D images as radial charts. The images show the one of a kind olfactory information for many complex odors, including those from explosives, contraband drugs of abuse, hazardous chemicals, and life-forms. Topics covered include chemical profiling; the zNose Model 4200's solid-state SAW detector, which can detect quantities as tiny as 1pg; ZNose Model 4200's operation with explosive odors and contraband; and the advantages of zNose 4200, including the ability of one zNose 4200 to create an unlimited number of virtual chemical sensors.