Tienta Sciences' SpectRIM Slide and BioStorage Technologies' Intelligent Specimen Inventory Storage System (ISISS) are among biotechnology activities ongoing in Indiana. The tools highlighted are meant to break up the logjam in drug discovery that has plagued efforts to locate of protein targets. The SpectRIM Slide substrate is a chemically inert, hydrophobic, stainless steel surface for measurement of small amounts of material, particularly from dilute solutions in polar solvents, including water. The SpectRIM Slide is based on Raman spectroscopy and identifies post-translational modifications of proteins. The SpectRIM Slide does not destroy protein samples, while chromatography and mass spectroscopy do. Surface materials do not interfere with Raman spectroscopy, which measures molecular vibrations. A sample applied to the SpectRIM Slide can be measured by Raman spectroscopy and also by infrared spectroscopy and MALDI mass spectroscopy. SpectRIM Slide can detect the structure of a drug in minutes and can prevent the loss of a full production batch, says Tienta. Tienta is the first company funded by Inproteo, a commercial life science formed by Eli Lilly & Company, Purdue, University, and Indiana University. Indiana is working to strengthen its industrial economy through biotechnology, and newer companies are welcome at the Purdue Research Park in West Lafayette, Indiana.